Quiz Time!

amlove21

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So, just for giggles, I want all your medical geek opinions on a pt I saw recently.

You are conducting a MEDCAP in the Horn of Africa. A mother of three brings in her 20 month old African son. The mother states (through an interpreter) that about a month ago, the child "stopped wanting to eat. Even his favorite foods are left alone." As you talk to the mother, the child becomes agitated and scared, and crying. Produces tears and snot (cear) as he cries. In the course of the interview, child falls asleep. When asked if that is normal, the mother replies "He just does that. He gets exhausted from crying or playing, and just runs out of energy and goes to sleep." Mother reports he has some intermittent loose bowel/diarrhea, but is unable to say how many times a day he makes urine/fecal matter. She also states that he sleeps very well at night.

Upon inspection, the child seems to be undersized and slightly malnourished, but if you saw this child up and walking around, it would not "jump out" that he is malnourished. No signs of trauma, no significant med history because no doctors live where he does. Pt tracks personnel in the room prior to going to sleep, and interacted normally with the mother. HEENT intact and unremarkable. Intact brachial and pedal pulse, HR 110, cap refil -1, no turger, abdomen slightly distended, soft, and reveals no guarding, and the examination did not wake the patient. Lungs are equal and bilateral, with non labored breathing WNL. NSTR for the rest of the head to toe/interview. Reflexes normal. O2 sat normal (98 on ambient air). BGL is WNL. Temp is WNL.

You don't have access to a lab, so you're unable to draw/test labs. You don't have a CT scan or ultrasound because it's a field hospital.

Let's talk differential diagnosis and treatment.

Discuss!
 
Great post! Non-medical opinion: Rotavirus? I don't know how long it lasts. A month seems like a long time, and temp seems normal, so I am probably wrong. But that's my final answer.
 
Great post! Non-medical opinion: Rotavirus? I don't know how long it lasts. A month seems like a long time, and temp seems normal, so I am probably wrong. But that's my final answer.


Well, there is no "answer", just probability. I like where your head's at- most common cause of diarrhea in kids worldwide, developing country, fecal/oral transmissions (dirty hands touching food). PT was asymptomatic- no fever, vomiting, severe diarrhea, and definitely no pain in the abdomen. Usually the diarrhea and fever are intense in the first week. The maxim "The patient doesn't read the books and won't present how the books teach you" plays here, but gastroenteritis status post 1 month would be more pronounced, I think. Rota usually has an expiration date. I think I'd be pretty comfortable ruling it out.

Cool post. I am way off but I am thinking tapeworm

Parasitic infection made our top 3. While the child was asymptomatic, tapeworms and other worms of that family sometimes produce no symptoms. We couldn't rule it out completely, but if it was tapeworms I would assume his malnourishment would have been much more acute, especially after a month.
 
Wow that could be a hundred different things here in the USA, much less Africa. I don’t know my ass from a hole in the ground medically speaking, but I am trying to learn… Maybe look at the diet and see if any known food/water contaminations have taken place in the area. Possibly some form of a parasite? Are any other children having the same problems, any other patients with the same symptoms in the last 30+ days? And if so, what have they been eating, drinking, messing with...
 
Has the kid been eating any domestic animal fecal matter? What animals live in the hovel with the family?
What are the normal water sources? How fouled are they?
What are the locally endemic diseases besides AIDS? (trying to make the unicorns go away)

Just getting the better Hx to think
 
I'm gonna vere off from any infectious/parasitic cause and head down the gastric tract itself road. A otherwise apparently non-ill toddler that doesn't eat isn't hungry; likely from decreased gastric emptying so what little he does eat keeps him full longer. Now when you combo this with the lower GI intermittent diarrhea, I'm thinking either decreased intentinal motility or obstruction. I'd lean to some sort of obstruction (small bowel), causing a sort of "dam" effect upstream and the diarrhea is leaking around the obstruction. This will also have a negative effect on nutrient absorbtion causing the relatively (for the area) malnutrition hence the easy tiring.
 
African sleeping sickness.
I'll cosign on this one, although 1- the child has never traveled, and we didn't see any other cases of African Sleeping Sickness (ASS?! :hmm:). No period of fever, no joint pain, no swollen nodes or "Winterbottom's Sign" (characteristic swelling of the lymph nodes in the back of the neck).

Interesting, and I like it. The spleen didn't feel enlarged, and neither did the lymph nodes, but that's not a solid rule out. It would explain the lethargy and the delayed/non-acute symptoms.

Its Africa dude, I'm going with AIDs sadly.

Where we were had a very large (over 40%) AIDS rate, so it bears some thought. Although, usually full blown AIDS kills from infections (e.g- pneumonia) and HIV has very little discernable symptoms. A lab and a white cell count would be awesome, but no dice. Without those, it's very hard to diagnose HIV.

Has the kid been eating any domestic animal fecal matter? What animals live in the hovel with the family?
What are the normal water sources? How fouled are they?
What are the locally endemic diseases besides AIDS? (trying to make the unicorns go away)

Just getting the better Hx to think

In order- EVERYONE here has been eating domestic animal fecal matter, since the beginning of time. We considered Rota and Hanta (mice). Didn't scream "that's it", but cant rule it completely out. Mostly goats (sidebar- I saw a picture perfect ORF case. The lady was astounded I knew she lived with goats). Normal water source is the one and only well in town. CA tested their water a while back, and is was JUUUUUUST this side of potable. The villagers had some pretty good instruction on boiling water before drinking it, but again, we are getting information from the parent, so consider your source. Handwashing is simply not done. Local endemic diseases besides AIDS? It's a veritable "who's who". The main culprits- Unchecked TB, fungal infections, pink eye, everything/anything you can think of being bad. Here is a very long read, for starters (http://www.who.int/diseasecontrol_emergencies/toolkits/Hoa2.pdf).

I'm gonna vere off from any infectious/parasitic cause and head down the gastric tract itself road.

BANG! This is what I would diagnose with a gun to my head. Some sort of impaction (mechanical or otherwise) in the bowel, slowly building over time, and that's where we are now. This is what I personally concluded. I don't know if it's the answer, but it's the one I felt most comfortable with, even though the abdominal exam didn't seem to lead that way. CT would be awesome here, and I was dying for a closer look, but alas, no dice.

H.Pyllori? Just a guess since I had an episode that went undiagnosed for a very long time and presented similarly.


We had not thought of this one, but it is HAYOOG in Africa, especially in east Africa. Great catch, Rangermom! That's good work right there.
 
Wow, the domino effect of multiple low level endemics is astounding, coupled with the in utero infection/antibody array this is very interesting - and without the ability to perform the labs, makes it very difficult to hazard a Dx... the differential algorythym is mind boggling.

Has the kid eaten a stick/rock/piece of cloth and caused a physical blockage in the GI tract?
 
... Dx... the differential algorythym is mind boggling....

Has the kid eaten a stick/rock/piece of cloth and caused a physical blockage in the GI tract?
Tell me about it. The even worse part? I don't know when we are going back, and I wanted to come up with SOMETHING so I could get ABX, some sort of treatment for this kid. It's very likely this child is not going to be seen if he does have a serious problem. But I don't think you can just throw this kid some INANZ or Moxy or cipro and call it good.

We asked if he could have eaten rocks, something man made, all that stuff. Mother never saw that, but consider the source.
 
No signs of scratching or funny taste in his mouth (like metal)? What color is his urine? What's his mother's medical history? Anything she may have passed on?

Just reaching out there a little.

Do you think it could be something as "simple" as anemia? Then again, out in the Horn of Africa, how many people probably don't have anemia?
 
No signs of scratching or funny taste in his mouth (like metal)? What color is his urine? What's his mother's medical history? Anything she may have passed on?

Just reaching out there a little.

Do you think it could be something as "simple" as anemia? Then again, out in the Horn of Africa, how many people probably don't have anemia?
Mother didn't report any color for the urine. Mother has no idea what she has/doesn't have, as the only times she's ever seen a doctor had been because she was giving birth. Can't know what the kid was "tasting", he couldn't speak English (or Somali, or Arabic, or French), so dead end there.
 
Another one we thought through and it just wasn't adding up. We did talk about it, though, so you can pat yourself on the back for that one.
We thought maybe it was one of those things American kids get shots to prevent, like MMR, and moved past those in short order also.
 
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