It's kinda of a catch-22. People(aside from terminally online weirdos) don't mind women in action lead roles, but people don't really go see female-fronted action films unless it's an established IP or an ensemble cast. Tomb Raider and Resident Evil worked because of the games, and I think it's fair to say the Suicide Squad movies were a female-fronted ensemble.
The last big female led movie I can honestly think of was Kill Bill. Atomic Blonde was really good, but not very many people (comparatively) went to see it.
I think we'll see an increase of "From the World of" stories in franchises, because the original John Wick movies already established there are female assassins that kick ass. I think that'll be more palatable to people than gender-swapping main characters.